Iranian Journal of Neurosurgery
مجله جراحی مغز و اعصاب ایران
Iran J Neurosurg
Medical Sciences
http://irjns.org
1
admin
2423-6497
2423-6829
10.32598/irjns
en
jalali
1394
9
1
gregorian
2015
12
1
1
3
online
1
fulltext
en
Relationship of the P Angle with Stereotactic Arc in Intraoperative Outcome of Patients with Parkinson’s Disease Undergoing Deep Brain Stimulation
Gamma Knife Radiosurgery
Research
<p style="text-align: justify;"><strong>Background & Aim: </strong>DBS (deep brain stimulation) is a new and successful technique in treatment of symptoms of Parkinsonism especially after drug resistance. Research in this field is mostly designed for evolution of this technique. The present study aimed at evaluating the relationship between the angle formed in midsagittal and STN (sub-thalamic nucleus) axis line and recording length in the final electrode p lacement.</p>
<p style="text-align: justify;"><strong>Methods & Materials/Patients:</strong> 46 patient candidates for DBS operation were studied in terms of demographic variables, STN nucleus length, the angle between midsagittal line and STN axis (p angle), the number of tested electrodes, force and length of final electrode registration and final coordinates of the placed electrode. The primary information was obtained from patients records and other technical information based on MRI imaging using Stereonata software and during surgery. The information were analyzed using SPSS (version 16) and descriptive analysis and linear relationship.</p>
<p style="text-align: justify;"><strong>Results:</strong> The mean force of the recording from trial microelectrodes implanted in the right side ranged from 1.49 ± 1.45 to 2.65 ± 1.42 and in the left side from 1.53 ± 1.35 to 2.65 ± 2.30. In comparative analysis, no significant statistical relationship was found between P angle of the right side and degree registered in the final electrode of the right side (Pearson correlation: 0.314, P value= 0.049).</p>
<p style="text-align: justify;"><strong>Conclusion:</strong> Not only accurate electrodes positioning in the STN can lead to improved outcome within bilateral STN DBS, but also optimizing defined P angle can have beneficial effects on intraoperative outcome after STN DBS.</p>
Sub-thalamic Nucleus Axis, Mid-sagittal Line, Stereotactic, T2-weighted Coronal, Intraoperative Outcome, Parkinson, Deep Brain Stimulation
6
10
http://irjns.org/browse.php?a_code=A-10-100-27&slc_lang=en&sid=1
Mansour
Parvaresh
منصور
پرورش
10031947532846003016
10031947532846003016
No
MD, Assistant Professor of Neurosurgery, Neurosurgery Department, Iran University of Medical Sciences, Tehran, Iran
Maziar
Azar
مازیار
آذر
10031947532846003017
10031947532846003017
No
MD, Associate Professor of Neurosurgery, Neurosurgery Department, Iran University of Medical Sciences, Tehran, Iran
Babak
Alijani
بابک
علیجانی
10031947532846003018
10031947532846003018
Yes
MD, Assistant Professor of Neurosurgery, Neurosurgery Department, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Guilan, Iran