Iranian Journal of Neurosurgery
مجله جراحی مغز و اعصاب ایران
Iran J Neurosurg
Medical Sciences
http://irjns.org
1
admin
2423-6497
2423-6829
10.32598/irjns
en
jalali
1394
9
1
gregorian
2015
12
1
1
3
online
1
fulltext
en
Microscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents
Gamma Knife Radiosurgery
Research
<p style="text-align: justify;"><strong>Background & Aim: </strong>We described the presentation, management and subsequent treatment outcomes of children and adolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service as well as assessing long-term outcomes in terms of endocrine status and neurology symptoms.</p>
<p style="text-align: justify;"><strong>Methods & Materials/Patients:</strong> A total of 21 participants with histologically verified pituitary adenoma between January 2011 and June 2014 were studied. Patients' data from clinical, radiological and pathological records were analyzed using SPSS (Version 16).</p>
<p style="text-align: justify;"><strong>Results: </strong>All these children and adolescents with pituitary adenomas were managed with microscopic transsphenoidal surgery. The most common symptom was Cushing (47.6%, n=10). The functional type (76.2%, n=16) was more than the non-functional. The post-operative control MRI of most of them was clear (90.5%, n=19). The lab control of most of them was normal (76.2%, n=16). Apoplexy was seen in 5 patients (33.8%). Gross-total resection (GTR; 100% tumor removal as judged by early post-operative imaging) was achieved in 19 cases. Only one of these patients showed evidence of radiologic recurrence.</p>
<p style="text-align: justify;"><strong>Conclusion</strong>: In our study, all patients underwent microscopic transsphenoidal surgery due to limitation of endoscopic approach in pediatric and avoided wide anatomical deficit. Doing a comparative study between these two approaches will bring about promising results.</p>
Pediatric Pituitary Adenoma, Apoplexy, Transsphenoidal Approach, Functional Pituitary Adenomas, Nonfunctional Pituitary Adenomas
11
15
http://irjns.org/browse.php?a_code=A-10-100-28&slc_lang=en&sid=1
Masoud
Shirvani
مسعود
شیروانی
10031947532846003019
10031947532846003019
No
MD, Neurosurgeon, Department of Neurosurgery, Milad Hospital, Tehran, Iran
Alireza
Hajimirzabeigi
علیرضا
حاجی میرزابیگی
10031947532846003020
10031947532846003020
No
MD, Department of Neurosurgery, Milad Hospital, Tehran, Iran
Rozita
Jafari
رزیتا
جعفری
10031947532846003021
10031947532846003021
No
Surgeon, Department of Otolaryngology, Head and Neck Surgery, Tracheal Research Center, Shahid Beheshti University of Medical Sciences, Masih Daneshvari, Tehran, Iran
Morteza
Khatami
مرتضی
خاتمی
10031947532846003022
10031947532846003022
No
MD, Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Guilan, Iran
Alireza
Razzaghi
علیرضا
رزاقی
10031947532846003023
10031947532846003023
No
MSc in Epidemiology, Guilan Road Trauma Research Center, Poursina Hospital, Guilan University of Medical Sciences, Guilan, Iran
Shahrokh
Yousefzadeh-Chabok
شاهرخ
یوسف زاده چابک
10031947532846003024
10031947532846003024
Yes
MD, Professor of Neurosurgery, Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Guilan, Iran