en Brain Tumors Case report <div style="text-align: justify;"><strong>Background and Importance:</strong> Liponeurocytoma is a rare tumor of the CNS. Some of its prominent features include low neuronal proliferation with foci of lipomatous differentiation. So far, 70&nbsp;reports on cases of brain liponeurocytoma have been published. Most of them were located in the cerebellar hemisphere, but only 7 cases of primary Cerebellopontine Angle (CPA) liponeurocytoma&nbsp;have been reported.<br> <strong>Case Presentation: </strong>We presented a 27-year-old woman with a 6-month progressive headache and dizziness. More recently, she developed progressive hearing loss and ataxia. Pre-operative&nbsp;MRI of the brain demonstrated a heterogeneous solid extra-axial lesion in the right CPA with<br> hydrocephalus. The operation was performed via the retro sigmoid approach. Histopathological&nbsp;diagnosis was confirmed as liponeurocytoma. No radiotherapy was performed. The patient was&nbsp;followed up for two years. There were no signs of recurrence.<br> <strong>Conclusion: </strong>Liponeurocytoma is a rare tumor. In most of the cases, it is presented in the cerebellum, and the CPA as the primary location of this tumor is extremely uncommon. Typically, surgery is the treatment of choice for these lesions. If the tumor is subtotal, radiotherapy after operation and<br> resection can also be advantageous.<br> <br> <br> &nbsp;</div> Liponeurocytoma, Hearing loss, Cerebellopontine Angle (CPA), Ataxia 147 153 http://irjns.org/browse.php?a_code=A-10-262-3&slc_lang=en&sid=1 Seyed Ali Mousavinejad alimousavi65@yahoo.com 10031947532846005148 10031947532846005148 No Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ahmad Jabbari 10031947532846005149 10031947532846005149 No Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mahmoud Dehghan m.d21.9.1356@gmail.com 10031947532846005150 10031947532846005150 Yes Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Ira Kaveh Ebrahimzadeh 10031947532846005151 10031947532846005151 No Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Ira Kasra Amin Kazemi 10031947532846005152 10031947532846005152 No Department of Neurosurgery, Ayat Allah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran Jouan Taheri Talesh 10031947532846005153 10031947532846005153 No Department of Neurosurgery, Ayat Allah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran Omidvar Rezaei 10031947532846005154 10031947532846005154 No Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran