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Sungkaro K, Sae-heng S. Metastasis of Malignant Intracranial Meningioma to the Lung: Report of a Case and Review of the Relevant Literature. Iran J Neurosurg 2022; 8 :9-9
URL: http://irjns.org/article-1-306-en.html
1- Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand , kanisorn7640@gmail.com
2- Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand
Abstract:   (545 Views)
Background and Importance: Distant extracranial metastasis of meningioma is rare, and the pathophysiology of metastasis in meningioma remains a topic of debate. This study aimed to describe a patient who suffered from multiple pulmonary metastases of meningioma.
Case Presentation: This report introduced a rare case of a 47-year-old female who presented with right hemiparesis. Cranial Computed Tomography (CT) demonstrated a homogeneously enhanced tumor in the left temporal lobe. The patient underwent tumor resection; the pathological result was found to be World Health Organization (WHO) grade I meningothelial meningioma. Recurrence of the tumor transpired after two years and a second operation was performed. WHO grade II atypical meningioma was diagnosed. Subsequently, the patient developed a chronic cough and her chest x-ray showed multiple lung masses. CT-guided biopsy of the right lung mass was performed. Finally, pulmonary metastatic meningioma was diagnosed.
Conclusion: Distant extracranial metastasis and malignant transformation of meningioma involve the genetic alteration of a tumor, which should be studied further.
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Type of Study: Case report | Subject: Brain Tumors

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