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Iran J Neurosurg 2023, 9 - Continuous Publishing: 0-0 |
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Boukassa L, Ekouele-Mbaki H B, Ibara Wame R, Ngackosso O B, Kinata Bambino S B, Mouamba F G, et al . Histological Aspects of the Dural Crossing of Arteries to the Brain in the Fetus. Iran J Neurosurg 2023; 9 : 26
URL: http://irjns.org/article-1-355-en.html
URL: http://irjns.org/article-1-355-en.html
Leon Boukassa * 
1, Hugues Brieux Ekouele-Mbaki2 , Ruth Ibara Wame2 , Olivier Brice Ngackosso2 , Sinclair Brice Kinata Bambino3 , Fabien Gael Mouamba2 , Rel Boukaka Kala2 , Gédeon Colin Thouassa2
1, Hugues Brieux Ekouele-Mbaki2 , Ruth Ibara Wame2 , Olivier Brice Ngackosso2 , Sinclair Brice Kinata Bambino3 , Fabien Gael Mouamba2 , Rel Boukaka Kala2 , Gédeon Colin Thouassa2
1- Department of Doctoral Training, Faculty of Health Sciences, Brazzaville University Hospital Center, Brazzaville, Congo. , lboukassalouf@gmail.com
2- Department of Doctoral Training, Faculty of Health Sciences, Brazzaville University Hospital Center, Brazzaville, Congo.
3- Faculty of Health Sciences, Brazzaville University Hospital, Brazzaville
2- Department of Doctoral Training, Faculty of Health Sciences, Brazzaville University Hospital Center, Brazzaville, Congo.
3- Faculty of Health Sciences, Brazzaville University Hospital, Brazzaville
Abstract: (1251 Views)
Background and Aim: This study aims to determine the histological evolution of the relationship between the dura mater and the walls of the arteries with the encephalic destination in fetuses of different ages.
Methods and Materials/Patients: We conducted a prospective descriptive study over 4 months. It included eight fetuses aged between 24 and 34 weeks of amenorrhea obtained after informed consent from the parents. Four fetuses were less than 30 weeks old and four were more than 30 weeks old. After the previously formalized anatomical dissection of the fetal skull base, partial pairs of the internal carotid and vertebral arteries were removed at the level of the dural crossing. Samples were fixed with 10% formalin and embedded in paraffin before routine histochemical (hematoxylin-eosin) and immunohistochemical (matrix metalloproteinase 7 [MMP7]) staining.
Results: We observed a "separation zone" between the dura mater and the arterial wall that is complete in fetuses between 24 and 29 weeks gestation. This cleavage zone disappeared in fetuses of 30 weeks gestation and more. This dural-arterial contact, observed from this age onwards, bears witness to a progressive arterial "invasion" by the dura mater, to reach the aspect observed in adults, characterized by the penetration of dural fibers into the arterial wall.
Conclusion: The duro-arterial relationship at the intersection level is a dynamic phenomenon that has been going on since the antenatal period.
Methods and Materials/Patients: We conducted a prospective descriptive study over 4 months. It included eight fetuses aged between 24 and 34 weeks of amenorrhea obtained after informed consent from the parents. Four fetuses were less than 30 weeks old and four were more than 30 weeks old. After the previously formalized anatomical dissection of the fetal skull base, partial pairs of the internal carotid and vertebral arteries were removed at the level of the dural crossing. Samples were fixed with 10% formalin and embedded in paraffin before routine histochemical (hematoxylin-eosin) and immunohistochemical (matrix metalloproteinase 7 [MMP7]) staining.
Results: We observed a "separation zone" between the dura mater and the arterial wall that is complete in fetuses between 24 and 29 weeks gestation. This cleavage zone disappeared in fetuses of 30 weeks gestation and more. This dural-arterial contact, observed from this age onwards, bears witness to a progressive arterial "invasion" by the dura mater, to reach the aspect observed in adults, characterized by the penetration of dural fibers into the arterial wall.
Conclusion: The duro-arterial relationship at the intersection level is a dynamic phenomenon that has been going on since the antenatal period.
Article number: 26
Type of Study: Research |
Subject:
Neuroscience
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Owned by Guilan University of Medical Sciences.
Co-published by Negah Institute for Scientific Communication.
Contact Information:
IrJNS Office, Guilan Road Trauma Research Center, Poursina Hospital, Namjoo St, Rasht, Guilan, Iran.
Publisher Tel : +9821 45355555 , 45355000
Email: ir.journalofneurosurgery@gmail.com, info@irjns.org
Owned by Guilan University of Medical Sciences.
Co-published by Negah Institute for Scientific Communication.
Contact Information:
IrJNS Office, Guilan Road Trauma Research Center, Poursina Hospital, Namjoo St, Rasht, Guilan, Iran.
Publisher Tel : +9821 45355555 , 45355000
Email: ir.journalofneurosurgery@gmail.com, info@irjns.org
