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Pakseresht Mogharab M, Behzadnia H, Alijani B, Reihanian Z, Andalib S. Impact of Age on Neurosurgical Outcomes and Complications in Intracranial Meningioma. Iran J Neurosurg 2024; 10 : 30
URL: http://irjns.org/article-1-457-en.html

Background and Aim: Despite advancements in neuroimaging and surgical techniques, the management of meningioma in older patients remains challenging. In this study, we aimed to compare the impact of age on complications and outcomes of surgical resection of intracranial meningioma.
Methods and Materials/Patients: This retrospective cohort used medical records of 62 patients
with confirmed intracranial meningioma who underwent surgical removal including 31 patients aged 18 to 65 (group 1) and 31 patients aged 65 and older (group 2). Demographic data along with discharge and six-month post-surgery Glasgow Outcome Scale (GOS) scores and complications were collected and compared between the two groups.
Results: Group 1 included 8(42.11%) males and 23(53.49%) females with a mean age of 44.39±6.44 years. Group 2 had 11(57.89%) males and 20(46.51%) females with a mean age of 68.65±4.54 years. The discharge and overall six-month mortality rate were 0% in group 1 and 6.45% in group 2.
Unfavorable outcomes (GOS scores of 2 and 3) were seen in 1(3.23%) of the younger and 1(3.45%) of the older groups. The prevalence of the recorded postoperative complications was 9.68% (peritumoral edema), 8% (cerebral hemorrhage), and 4.84% (wound infection) of the participants.
There was no statistical difference between the study groups concerning postoperative mortality rate, outcomes, or complications.
Conclusion: Our results suggest that age does not increase the incidence of mortality, unfavorable outcomes, or surgical complications following meningioma removal. Regardless of age, proper patient selection for meningioma surgery may lead to favorable outcomes.