Background and Importance: Our learning curve during two decades of neurosurgical practice has been changed from an abstractive to a more meaningful and conductive state. In cases of fifth nerve neurinoma, pre-operative anatomopathologic diagnosis could lead us to a pre-planned program during and after the surgery to get the safe surgical result.

Case Presentation: Representation of two complex fifth nerve neurinoma cases, untoward happenings and the way to manage patient safety. Review of literature to find a wise approach for maximum benefit is included here.

Conclusion: Both of our patients have developed iatrogenic unilateral corneal anesthesia, one of them warned of it and the second one not. We have had more problems in the way of preservation of the cornea in the warned case. We have reviewed the factors influencing safe corneal preservation after the operation of fifth nerve neurinoma which are included following items: surgical approach, Anatomopathologic location of the tumor (pre-ganglionic, ganglionic or post-ganglionic), simultaneous damage of V and VII nerve including vidian nerve, preserved corneal sensation, any combination of injury to physiologic and mechanical protectors. The cornerstones to have a safe cornea following such surgeries are pre-operative exam of fifth and 7th nerve in all aspects and also early post-operative evaluation of them including the state of the tear secretion. We encounter corneal anesthesia and epithelial defect. Iatrogenic damage of vidian nerve depending to approach selected seems to be considerable. Simultaneous damage of V and VII nerve during the surgery of large neurinoma are expected and noteworthy.

Background and Importance: Lumboperitoneal shunts are commonly used to treat several conditions, but their use can result in significant complications. We discuss a complication of these shunts that has not been reported in the literature to date.
Case Presentation: An obese, 41-year-old woman admitted to Rasool Akram Hospital complaining of a severe headache and blurred vision. The physical examination indicated that she had papilledema, and a lumbar puncture demonstrated cerebrospinal fluid opening pressure of 33 cm of H2O. Pseudotumor Cerebri was diagnosed, and the patient underwent surgery to insert a lumboperitoneal (LP) shunt. She suffered from severe headaches and nausea during the post-operative period. The post-operative syndrome was misdiagnosed as shunt-induced cerebellar tonsillar ptosis; however, further evaluation indicated that intracranial chronic subdural hematoma, a very rare complication subsequent to lumboperitoneal shunting, was the cause of the post-operative syndrome. Subdural hematoma was evacuated and her symptoms disappeared thereafter. 
Conclusion: Persistent symptoms, such as headache, nausea, and vomiting, after placement of a lumboperitoneal shunt should be taken serious, and imaging, such as a CT of the brain, should be done to rule out subdural hematoma.