Keshav Mishra, Somnath Sharma, Devendra K. Purohit, Arpita Jindal,
Volume 7, Issue 2 (4-2021)
Abstract
Background and Importance: Chondrosarcoma is a rare malignant cartilage forming tumor, usually arising from long bones and rarely observed in the cranium. In the cranium, it commonly arises from the skull base with the skull vault being a highly unusual site.
Case Presentation: We present the case of a 30-year female presenting with complaints of headache for 6 months. The patient was found to have large chondrosarcoma in the right frontoparietal region, which is an extremely rare location. The final diagnosis was based on histological examination, suggestive of well-differentiated chondrosarcoma [the World Health Organization (WHO); grade I].
Conclusion: Cranial vault chondrosarcoma is an uncommon histological diagnosis with surgery as the primary treatment option; however, adjuvant radiotherapy plays a definitive role, especially in aggressive or incomplete removed cases.
Seyed Amir Hossein Javadi, Seyed Morsal Mosallami Aghili, Amir Mohammad Javadi, Samira Raminfard,
Volume 8, Issue 0 (8-2022)
Abstract
Background and Aim: Diffusion Tensor Imaging (DTI)-based tractography can help us visualize the spatial relation of fiber tracts to brain lesions. Several factors may interfere with the procedure of diffusion-based tractography, especially in brain tumors. The current study aims to discuss several solutions to improve the procedure of fiber reconstruction adjacent to or inside brain lesions. Illustrative cases are also presented.
Methods and Materials/Patients: The paper is a narrative review of methods that can improve DTI-based fiber reconstruction in the area of brain tumors. To provide up-to-date information, we briefly reviewed related articles extracted from Google Scholar, Medline, and PubMed.
Results: We proposed five techniques to improve fiber reconstruction. Technique 1 is a very low Fractional Anisotropy (FA) application. Technique 2 includes resampling techniques, such as q-ball and High Angular Resolution Diffusion Imaging (HARDI). Technique 3 is the reconstruction of fiber tracts by defining the separated Region of Interest (ROIs). Technique 4 explains the selection of the ROIs according to functional Magnetic Resonance Imaging (fMRI) since the anatomical configuration is distorted by neoplasm. Technique 5 consists of using unprocessed images for preoperative planning and correlation with the clinical situation.
Conclusion: DTI tractography is highly sensitive to noise and artifacts. The application of tractography techniques can improve fiber imaging in the area of brain tumors and edema.
