Volume 4, Issue 1 (Winter 2018)                   Iran J Neurosurg 2018, 4(1): 51-55 | Back to browse issues page


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Alijani B, Yousefzadeh-Chabok S, Ramzannejad A, Behzadnia H, Emamhadi M. Simultaneous Diffuse Idiopathic Hyperostosis, Ossification of the Posterior Longitudinal Ligament and Ligamentum Flavum. Iran J Neurosurg 2018; 4 (1) :51-55
URL: http://irjns.org/article-1-122-en.html
1- Department of Neurosurgery, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran.
2- Neuroscience Research Center, Guilan University of Medical Sciences, Rasht, Iran.
3- Department of Neurosurgery, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran. , dr.behzadnia@yahoo.com
4- Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Abstract:   (4465 Views)
Background and Importance: A 60-year-old diabetic man with simultaneous diffuse idiopathic hyperostosis, massive ossification of the posterior longitudinal ligament and cervical and higher part of thoracic ligamentum flavum is reported in this article. Such comorbidity rarely occurs.
Case Presentation: The patient’s chief complaint was sensation abnormalities without gait disturbance or severe cord compression symptoms despite the advanced stage of the disease. Computed tomography scan and magnetic resonance imaging confirmed multi-level involvement of cervicothoracic spine.
Conclusion: After surgical treatment, his symptoms resolved completely with no complication.
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Type of Study: Case report | Subject: Spine

References
1. Storch MJ, Hubbe U,Golcker FX. Cervical myelopathy cause by soft-tissue mass in diffuse idiopathic skeletal hyperostosis. European Spine Journal. 2008; 17(2):243-47. [DOI:10.1007/s00586-007-0508-6] [PMID] [PMCID] [DOI:10.1007/s00586-007-0508-6]
2. Guo Q, Ni B, Yang J, Zhu Z, Yang J. Simultaneous ossification of the posterior longitudinal ligament and ossification of the ligamentum flavum causing upper thoracic myelopathy in DISH: Case report and literature review. European Spine Journal. 2011; 20(2):195–201. [DOI:10.1007/s00586-010-1538-z] [PMID] [PMCID] [DOI:10.1007/s00586-010-1538-z]
3. Choi BW, Song KJ, Chang H . Ossification of the posterior longitudinal ligament: A review of literature. Asian Spine Journal. 2011; 5(4):267-76. [DOI:10.4184/asj.2011.5.4.267] [PMID] [PMCID] [DOI:10.4184/asj.2011.5.4.267]
4. Ahn DK, Lee S, Moon SH, Boo KH, Chang BK, Lee JI . Ossification of the ligamentum flavum. European Spine Journal. 2014; 8(1):89-96. [DOI:10.4184/asj.2014.8.1.89] [PMID] [PMCID] [DOI:10.4184/asj.2014.8.1.89]
5. Resnick D, Guerra J Jr, Robinson CA, Vint VC .Association of Diffuse Idiopathic Skeletal Hyperostosis (DISH) and calcification and ossification of the posterior longitudinal ligament. American Journal of Roentgenology. 1978; 131(6):1049–53. [DOI:10.2214/ajr.131.6.1049] [PMID] [DOI:10.2214/ajr.131.6.1049]
6. Fox TP, Desai MK, Cavenagh T, Mew E. Diffuse idiopathic skeletal hyperostosis: A rare cause of dysphagia and dysphonia. BMJ Case Reports. 2013; 202(6): 938-42. [DOI: 10.1136/bcr-2013-008978] [PMID] [PMCID] [DOI:10.1136/bcr-2013-008978]
7. Shiguematsa YF, Souza ECC, Zimmermann AF, Castro GRW, Pereira IA, Neves FS. Thoracic myelopathy due to calcification of the ligamentum fl avumwith hyperproteinorachia and responsive to steroid therapy: Case report. Revista Brasileira de Reumatologia. 2012; 52(3):438-46. [DOI:10.1590/S0482-50042012000300013] [DOI:10.1590/S0482-50042012000300013]
8. Littlejohn GO, Smythe HA. Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis. The Journal of Rheumatology. 1981; 8(6):965-68. [PMID]
9. Littlejohn GO, Smythe HA. Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis. The Journal of Rheumatology. 1981; 8(6):965-68. [PMID]
10. Tsuyama N. Ossification of the posterior longitudinal ligamentof the spine. Clinical Orthopaedics and Related Research. 1984; (184):71-84. [PMID] [PMID]
11. Wang MY, Thambuswamy M. Ossification of the posteriorlongitudinal ligament in non-Asians: Demographic, clinical, and radiographic findings in 43 patients. Neurosurg Focus. 2011; 30(3):E4. [DOI:10.3171/2010.12.FOCUS10277] [PMID] [DOI:10.3171/2010.12.FOCUS10277]
12. Koga H, Sakou T, Taketomi E, Hayashi K, Numasava T, Harata S. Genetic mapping of ossification of the posterior longitudinal ligament of the spine.The American Journal of Human Genetics. 1998; 62(6):1460-7. [DOI:10.1086/301868] [PMID] [PMCID] [DOI:10.1086/301868]
13. Kon T, Yamazaki M, Tagawa M, Tagawa M, Goto S, Terakado A, et al. Bone morphogenetic protein-2 stimulates differentiation of cultured spinal ligament cells from patients with ossification of the posterior longitudinal ligament. Calcified Tissue International. 1997; 60(3):291-6. [DOI:10.1007/s002239900231] [PMID] [DOI:10.1007/s002239900231]
14. Kawaguchi Y, Furushima K, Sugimori K, Inoue I, Kimura T. Association between polymorphism of the transforming growth factor-beta1 gene with the radiologic characteristic and ossification of the posterior longitudinal ligament. Spine. 2003; 28(13):1424-6. [DOI:10.1097/01.BRS.0000068245.27017.9F] [DOI:10.1097/01.BRS.0000068245.27017.9F]
15. Pal B. Rheumatic disorders and bone problems in Diabetes Mellitus. In: Williams G, Pickup JC, (Eds), Handbook of diabetes. Hoboken, New Jersey: Wiley-Blackwell; 2004
16. Song J, Mizuno J, Hashizume Y, Nakagawa H. Immunohistochemistry of symptomatic hypertrophy of the posterior longitudinal ligament with special reference to ligamentous ossification. Spinal Cord. 2006; 44(9):576-81. [DOI:10.1038/sj.sc.3101881] [PMID] [DOI:10.1038/sj.sc.3101881]
17. Ghosh B, Kishore S, Vijay V, Ramachandran A. Diffuse Interstitial Skeletal Hyperostosis (DISH) in type 2 diabetes. The Journal of the Association of Physicians of India. 2004; 52:994-6. [PMID]
18. Taurog JD. Ankylosing spondylitis, reactive arthritis, and undifferentiated spondyloarthropathy. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, (Eds), Harrison's principles of internalmedicine. Pennsylvania: McGraw-Hill; 1998.
19. Verlaan JJ, Boswijk BJ, de Ru JA, Dhert WJR, Oner FC. Diffuse idiopathic skeletal hyperostosis of the cervical spine: An underestimated cause of dysphagia and airway obstruction. The Spine Journal. 2011; 11(11):1058-67. [DOI:10.1016/j.spinee.2011.09.014] [PMID] [DOI:10.1016/j.spinee.2011.09.014]
20. Hashizume Y, Iijima S, Kishimoto H, Yanagi T. Pathology of spinal cord lesions caused by ossification of the posterior longitudinal ligament. Acta Neuropathologica. 1984; 63(2):123-30. [DOI:10.1007/BF00697194] [PMID]
21. Sreedharan S, Li YH. Diffuse idiopathic skeletal hyperostosis with cervical spinal cord injury: A report of 3 cases and a literature review. ANNALS Academy of Medicine Singapore. 2005; 34(3):257-61. [PMID] [PMID]
22. Westerveld LA, Verlaan JJ, Oner FC. Spinal fractures in patients with ankylosing spinal disorders: A systematic review of the literature on treatment, neurological status and complications. European Spine Journal. 2009; 18(2):145-56. [DOI:10.1007/s00586-008-0764-0] [PMID] [PMCID] [DOI:10.1007/s00586-008-0764-0]
23. Ghani I. Functional outcome in dish asssociated with Opll and Dens Hypertrophy resulting in rapidly progressive hemiplegia: A case report. Journal of Spine. 2014; 3(191):2. [DOI:10.4172/2165-7939.1000191] [DOI:10.4172/2165-7939.1000191]

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