Mohammadhosseini E, Aminmansour B, Andalibi S, Derakhshan M, Farokhpour F. Concomitant Primary Cerebral Lymphoma and Meningioma. Iran J Neurosurg 2019; 5 (1) :43-50
URL:
http://irjns.org/article-1-148-en.html
1- MD. Department of Neurosurgery, AL-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran , ehsan_m_h76@yahoo.com
2- MD. Department of Neurosurgery, AL-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
3- MD. Department of Radio Oncology, Omid Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
4- MD. Department of Pathology, AL-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract: (4174 Views)
Background and Aim: Primary central nervous system lymphoma (PCNSL) is a rare cancer confined to the brain, spinal cord, leptomeninges and eyes. The origin of this type of lymphoma is often type B lymphocytes, and because the central nervous system (CNS) has no lymph nodes or lymphatic vessels, the cause of PCNSL is still unclear. But its source appears to be from lymphocytes located in the CNS. This type of lymphoma has been reported in the context of congenital or acquired immune deficiency such as Wiskott Aldrich syndrome, kidney transplantation, and in particular AIDS. Frontal lobes are the most common sites of involvement in CNS.
Case Presentation: The patient was a 55-year-old man who had been referred to the Emergency Department of Al-Zahra Hospital, Isfahan, Iran due to recurrent headaches, nausea, and vomiting since 6 months ago.
Conclusion: Meningiomas are often benign and slowly growing tumors that originate from the arachnoid cap cell of meninges. Due to the rarity of concomitance of primary cerebral lymphoma and meningioma, there is no possibility of epidemiological studies in these patients.
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Highlights
● Concomitant primary cerebral lymphoma and meningioma is a rare type of CNS cancer with no predictable pattern of recurrence, therefore, any information on this matter may help scientists in the fields of neurosurgery and epidemiology.
● As the early diagnosis could increase the five year survival of newly diagnosed patients by 70%, symptoms which vary depending on the site of the tumor, should be taken under serious consideration.
● If suspected, detailed paraclinical examinations including CT scan, MRI, blood biomarkers, and histopathological studies are recommended.
Plain Language Summary
Primary cerebral lymphoma is a rare type of brain tumor arising from type B lymphocytes. Although it is very rare, it can also be superimposed to other types of brain tumors, like meningiomas. In this case it is hard to come to an accurate diagnosis.
Type of Study:
Case report |
Subject:
Brain Tumors