Volume 2, Issue 2 (9-2016)                   Iran J Neurosurg 2016, 2(2): 20-23 | Back to browse issues page

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Capozza M, Pansini G, Buccoliero A M, Barbagli G, Ashraf-Noubari B, Mariotti F et al . Foreign Body Reaction Mimicking Intracranial Abscess following the Use of Oxidized Regenerated Cellulose (SurgicelTM): Case Report and Literature Review. Iran J Neurosurg. 2016; 2 (2) :20-23
URL: http://irjns.org/article-1-40-en.html
1- MD, Department of Neurosurgery, University of Florence, Italy
2- MD, Neurosurgical Unit, Careggi General Hospital, Florence, Italy
3- MD, Unit of Pathology, Meyer Hospital, Florence, Italy
Abstract:   (5766 Views)

Background & Importance: The use of local hemostatic agents in neurosurgery is mandatory in order to control the sequelae of intracerebal hemorrhage. It is widely used in oxidized regenerated cellulose (Surgicel™).
Case Presentation: A 54-year-old man previously operated for grade II meningioma came back to our attention due to the onset of left side arm weakness one month after surgery. The CT scan and MRI showed an extensive lesion on the surgical site with the suspect of intracranial abscess. Intraoperative detections suggested the features of a granulomatous foreign body reaction.
Conclusion: The occurrence of granulomatous reaction to oxidized regenerated cellulose, when used as hemostatic agent, is a very rare finding following intracranial surgery.

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Type of Study: Case report | Subject: Gamma Knife Radiosurgery

1. Bjorenson JE, Grove HF, List MG Sr, et al. Effects of hemostatic agents on the pH of body fluids. Journal of Endodontists. 1986;12(7):289-92. [DOI:10.1016/S0099-2399(86)80110-8]
2. Buckley SC, Broome JC. A foreign body reaction to Surgicel (R) mimicking an abscess or tumor recurrence. British Journal of Neurosurgery. 1995;9(4):561-3. [DOI:10.1080/02688699550041241]
3. Chater-Cure G, Fonnegra-Caballero A, Baldión-Elorza AM, Jimenez-Hakim E. Gossypiboma in neurosurgery. Case report and literature review. Neurocirugia (Asturias, Spain). 2009;20(1):44-8. https://doi.org/10.4321/S1130-14732009000100006 [DOI:10.1016/S1130-1473(09)70193-9]
4. Ereth MH, Schaff M, Ericson EF, et al. Comparative safety and efficacy of topical hemostatic agents in a rat neurosurgical model. Neurosurgery. 2008;63(4 Suppl 2):369-72. [PMID]
5. Feldman RP, Marcovici A, Suarez M, Goodrich JT. Foreign body granuloma mimicking intracranial meningioma: case report and review of the literature. Neurosurgery. 1999;44(4):855-8. [DOI:10.1097/00006123-199904000-00091] [PMID]
6. Hara N. Intracranial foreign-body granuloma caused by oxidized cellulose. Acta Neurochir (Wien) 1996;138(12):1468-9. [DOI:10.1007/BF01411128]
7. Ito H, Onishi H, Shoin K, et al. Granuloma caused by oxidized cellulose following craniotomy. Acta Neurochir (Wien). 1989;100(1-2):70-3. [DOI:10.1007/BF01405278]
8. Kothbauer KF, Jallo GI, Siffert J, et al. Foreign body reaction to hemostatic materials mimicking recurrent brain tumor. Report of three cases. Journal of Neurosurgery. 2001;95(3):503-6. [DOI:10.3171/jns.2001.95.3.0503] [PMID]
9. Ribalta T, McCutcheon IE, Neto AG, et al. Textiloma (gossypiboma) mimicking recurrent intracranial tumor. Archive of Pathology Laboratory Medicine. 2004;128(7):749-58. [PMID]
10. Sandhu GS, Elexpuru-Camiruaga JA, Buckley S. Oxidized cellulose (Surgicel) granulomata mimicking tumor recurrence. British Journal of Neurosurgery. 1996;10(6):617-9. [DOI:10.1080/02688699646989] [PMID]
11. Spiller M, Tenner MS, Couldwell WT. Effect of absorbable topical hemostatic agents on the relaxation time of blood: an in vitro study with implications for postoperative magnetic resonance imaging. Journal of Neurosurgery. 2001;95(4):687-93. [DOI:10.3171/jns.2001.95.4.0687] [PMID]
12. Young ST, Paulson EK, McCann RL, Baker ME. Appearance of oxidized cellulose (Surgicel) on postoperative CT scans: similarity to postoperative abscess. AJR. American Journal of Roentgenology. 1993;160(2):275-7. [DOI:10.2214/ajr.160.2.8424333] [PMID]

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