Background & Importance: Our study was performed based on the first case, reported in English, of a patient with three contemporary lesions, an extra-axial malformation and two vascular ones.
Case Presentation: A 62-year-old man referred to our clinic due to right hand tremor associated to a slowing of idea-forming function and movements. The neuroradiological evidence showed a right fronto-temporal meningioma with the contemporary presence of an arteriovenous malformation (AVM) and of an aneurysm. The neuroradiological finding showed, also, a presumably “flow-related” right carotid-ophthalmic aneurysm with two millimeters in size. We performed the meningioma excision by the usage of cavitron ultrasonic surgical aspirator (CUSA), after the isolation of the sylvian fissure with the microdoppler and the removal of the AVM by the Hashimoto technique. Considering the very small size of the aneurysm, we decided to leave it in site. 
Conclusion: The post-operative examination showed a complete removal of the lesions, meningioma and AVM. We performed an exhaustive review of the current literature, and the result encompassed only another case, written in Japanese, about the contemporary presence of these three lesions.

Background & Importance: The use of local hemostatic agents in neurosurgery is mandatory in order to control the sequelae of intracerebal hemorrhage. It is widely used in oxidized regenerated cellulose (Surgicel™).
Case Presentation: A 54-year-old man previously operated for grade II meningioma came back to our attention due to the onset of left side arm weakness one month after surgery. The CT scan and MRI showed an extensive lesion on the surgical site with the suspect of intracranial abscess. Intraoperative detections suggested the features of a granulomatous foreign body reaction.
Conclusion: The occurrence of granulomatous reaction to oxidized regenerated cellulose, when used as hemostatic agent, is a very rare finding following intracranial surgery.