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Relationship of the P Angle with Stereotactic Arc in Intraoperative Outcome of Patients with Parkinson’s Disease Undergoing Deep Brain Stimulation
Mansour Parvaresh, Maziar Azar, Babak Alijani,
Volume 1, Issue 3 (12-2015)
Abstract

Background & Aim: DBS (deep brain stimulation) is a new and successful technique in treatment of symptoms of Parkinsonism especially after drug resistance. Research in this field is mostly designed for evolution of this technique. The present study aimed at evaluating the relationship between the angle formed in midsagittal and STN (sub-thalamic nucleus) axis line and recording length in the final electrode p lacement.

Methods & Materials/Patients: 46 patient candidates for DBS operation were studied in terms of demographic variables, STN nucleus length, the angle between midsagittal line and STN axis (p angle), the number of tested electrodes, force and length of final electrode registration and final coordinates of the placed electrode. The primary information was obtained from patients records and other technical information based on MRI imaging using Stereonata software and during surgery. The information were analyzed using SPSS (version 16) and descriptive analysis and linear relationship.

Results: The mean force of the recording from trial microelectrodes implanted in the right side ranged from 1.49 ± 1.45 to 2.65 ± 1.42 and in the left side from 1.53 ± 1.35 to 2.65 ± 2.30. In comparative analysis, no significant statistical relationship was found between P angle of the right side and degree registered in the final electrode of the right side (Pearson correlation: 0.314, P value= 0.049).

Conclusion: Not only accurate electrodes positioning in the STN can lead to improved outcome within bilateral STN DBS, but also optimizing defined P angle can have beneficial effects on intraoperative outcome after STN DBS.


Mental Health and Quality of Life in Parkinson Patients During the COVID-19 Epidemic: A Systematic Review
Farzin Bagheri Sheykhangafshe, Maryam Saeedi, Alireza Alesadi Sani, Arina Kiani, Vahid Savabi Niri,
Volume 8, Issue 1 (1-2022)
Abstract
Background and Aim: The COVID-19 has had several psychological and physical consequences, which have been more reported in people with chronic diseases, such as Parkinson’s Disease (PD). In this regard, this study reviewed all articles, which evaluated the mental health and quality of life of patients with PD during the COVID-19 epidemic.
Methods and Materials/Patients: In this study, the keywords Parkinson’s disease, PD, Coronavirus 2019, COVID-19, SARS-CoV-2, mental health, quality of life, depression, stress, and anxiety were searched in the abstract and title of articles published between 2020 (May) and 2022 (April) in reputable international scientific databases of EMBASE, Google Scholar, ScienceDirect, Scopus, and PsycINFO, PubMed, and Clarivate Analytics.
The PRISMA checklist was used to review and control the quality of articles. Of the total 369 articles found, 21 articles were selected for review.
Results: According to the studies, patients with PD had anxiety, depression, stress, poor sleep quality, death-related thoughts, fear, and cognitive, behavioral, and motor problems during the pandemic. Femininity, low level of education, and poverty were also among the factors exacerbating psychological disorders in PD patients. Decreased physical and social activity also reduced the quality of life in patients with PD. During home quarantine, many patients became concerned about access to medication and physicians, which
exacerbated PD.
Conclusion: According to studies, the outbreak of COVID-19 reduced the mental health and quality of life of patients with PD. Since having high mental health has an important role in increasing the immune system against various diseases, identifying and treating vulnerable groups can increase life expectancy in patients.

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