Abstract
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Highlights
● Acute Lung Injury (ALI) is relatively common after Traumatic Brain Injury (TBI) and 15% of patients with isolated moderate to severe TBI developed ALI.
● The frequency of patients who progressed to acute lung injury by the third day of hospitalization increased, compared to that of the first day. Moreover, the highest frequency respected the age group of 20-30 years (55.1%).
● The obtained results signified that on the third day, the highest frequency of acute lung injury concerned epidural hematoma (52%), Subdural Hematoma (SDH) (36%), and contusion (35.2%).
● The development of ALI is a critical independent factor affecting mortality in patients with traumatic brain injury, although this difference was not significant.
Plain Language Summary
Pulmonary complications, such as Acute Lung Injury (ALI) occur in 20%-25% of patients with isolated brain injury and have a poor prognosis. The present study aimed to determine the incidence of ALI in trauma patients who were admitted to Poursina Hospital. We aimed to assess the impact of ALI on mortality after isolated traumatic brain injury. Moreover, we intended to identify whether the development of ALI correlates with the severity of Traumatic Brain Injury (TBI). For this purpose, clinical data were collected in 2 years at Poursina Hospital. Our results addressed the highest frequency of ALI following TBI on the first day of hospitalization, in men (0.41%) in the age group of 40-50 years (7%) with severe brain damage (6%) and subdural hematoma (12%) following a motorcycle-car accident; on the third day of hospitalization, they were detected in men (43.8%) in the age group of 20-30 years (55%) with severe brain damage (42%) and epidural hematoma (52%), following a motorcycle accident. Besides, no significant correlation was observed between the incidence of ALI and mortality, the duration of hospitalization, Glasgow Coma Scale (GCS), mean head AIS score, or the extent of received blood units. The development of ALI is a critical independent factor affecting mortality in patients with TBI. According to the present study findings, men aged 20-30 years with severe cerebral injury, intra-parenchymal hemorrhage, and a motorcycle accident presented the highest rate of progression toward ALI during the first to third days of hospitalization.